What is bioactive glass?

Glass is used frequently in daily life, and it is quite impossible to get rid of glass. Glass is stable, proof to acid and alkali, and hard and durable. It is one of the raw materials required for most important equipment. In this article, we mainly focus on bioglass and make a comparison between the two.

Bioactive glass (BAG) has attracted wide attention in the fields of chemical materials and medicine due to its good biocompatibility, bioactivity, bone conductivity and degradability. At present, bioactive glass has been successfully used in the fields of bone injury and the treatment and repair of dental diseases. In this article, the composition and structure of biologically active glass, its preparation method, active mechanism and application in the field of bone repair and dentistry were described, and its development prospect was also prospected.

  1. Doesbioglass equal to bioactive glass?

The answer is yes. Bioglass (BG) or bioactive glass is a glass that can achieve specific biological and physiological functions. Bioglass is implanted into the bone defect site of the human body, and it can be directly combined with bone tissue to repair bone tissue and restore its function. Bioglass is invented by L.L. Henky from Florida University in 1969. Its main ingredients are approximately 45% Na2O, 25% CaO and 25% SiO2, and approximately 5% P2O5. If a small amount of other ingredients are added, such as K2O, MgO, CaF2, B2O3, etc., can obtain a series of practical biological glass. Using this glass to make human bones is much better than some metals.

  1. The characteristics of bioactive glass

BAG is a silicate glass composed of basic components such as SiO2, Na2O, CaO and P2O5. The significant feature of bioactive glass and glass ceramics is that the surface conditions change dynamically with time after implantation into the human body, and a bioactive hydroxyapatite (HCA) layer is formed on the surface, which provides a bonding interface for the tissue. Most bioactive glass is a Class A bioactive material, which has both osteoproductive and osteoconductive effects, and has good binding with bone and soft tissues.

  1. The application of bioactive glass

BAG is considered to be a good biological material applicable in the field of repair. The use of this repair material is not only extremely extensive, but also has irreplaceable magical effects on professional products, such as skin care, whitening and wrinkling, burns, oral ulcers, gastrointestinal ulcers, skin ulcers, and fungal killing , bone repair, bonding of soft tissue and bone tissue, etc. It is believed that its appearance will make an outstanding contribution to human health. In addition, BAG also has a fast surface response; the amorphous two-dimensional structure makes the strength and fracture toughness low; the elastic modulus (30-35MPa) is low, close to the cortical bone; and machinable bioglass has good processing performance.

  1. The prospects of  bioglass

BG, as a special composition and structure of glass, has good bone conductivity, biological activity and other biological properties. It has good development prospects. However, its performance is far from meeting the requirements of ideal bone graft materials, and people need to further optimize its component structure, improve performance, and expand its use. For example, the component structure of BG can be adjusted through the adjustment of components, the selection of precursors, and the optimization of the preparation process to improve its mechanical strength, degradation rate, or give it special functions. By combining with other modern preparation technologies, such as electricity Spinning, 3D printing technology, etc., preparing BGs with various morphologies and different spatial structures could inspire new uses.

Terms

Material

Materials are those that humans use to make goods, devices, components, machines, or other products, which include natural material and artificial material. Materials are substances, but not all substances can be called materials. Materials such as fuels and chemical materials, industrial chemicals, food and drugs are generally not considered as materials. However, this definition is not so strict. For example, solid rocket propellants are generally called “energetic materials” because they are part of artillery or rockets.

A living thing

A living thing with kinetic energy is also a collection of objects, while an individual creature refers to a living body, as opposed to a non-living body. Its elements include: under natural conditions, living objects with survivability and reproduction ability generated by chemical reactions and living offspring produced by it (or them) through reproduction, can respond to external stimuli accordingly , can be interdependent with the external environment and promote each other. In addition, it can excrete unnecessary substances in the body, and has the characteristics of inheritance and mutation.